
Helena Ljusberg-Wahren
Innovation developer

Phase behavior in the biologically important oleic acid/sodium oleate/water system
Author
Summary, in English
The phase behavior in the oleic acid/sodium oleate/normal saline (0.15 M NaCl aqueous solution) system has been determined. For this purpose visual inspection of samples between crossed polarizers, and Small Angle X-ray diffraction was used to identify the various phases and their unit cell dimensions. A rich phase behavior was observed for the ternary system, featuring reverse micellar, micellar cubic, hexagonal, and cubic phases, and large regions with lamellar phases. As expected the ratio the ‘oleic acid/sodium oleate’ determines the pH and as a consequence the phase behavior. The results could be modeled by an extended Henderson–Hasselbalch (HH) equation, which takes into account the electrostatic potential at the aqueous lipid interface. The knowledge obtained is important for understanding the lipolysis of triglycerides, as the phase behavior of the end-product of the reaction regulates how well the insoluble product can be dispersed and consequently the kinetics of the process.
Department/s
- Physical Chemistry
- LU Innovation
Publishing year
2018-03-01
Language
English
Pages
30-36
Publication/Series
Chemistry and Physics of Lipids
Volume
211
Links
Document type
Journal article
Publisher
Elsevier
Topic
- Physical Chemistry
Keywords
- Degree of dissociation
- Fatty acid pKa
- Lipolytic enzymes
- Liquid crystalline phases
- Oleic acid
- Small angle X-ray diffraction
- Sodium oleate
Status
Published
ISBN/ISSN/Other
- ISSN: 0009-3084